Articolo in rivista

Gene Therapy: The Role of Cytoskeleton in Gene Transfer Studies Based on Biology and Mathematics

Gene therapy is a promising approach for treating a wide range of human pathologies such as genetic disorders as well as diseases acquired over time. Viral and non-viral vectors are used to convey sequences of genes that can be expressed for therapeutic purposes. Plasmid DNA is receiving…

Thin film precursor formation during capilary penetration in microchannels

Gene Regulatory Network Modeling of Macrophage Differentiation Corroborates the Continuum Hypothesis of Polarization States

Macrophages derived from monocyte precursors undergo specific polarization processes which are influenced by the local tissue environment: classically-activated (M1) macrophages, with a pro-inflammatory activity and a role of effector cells in Th1 cellular immune responses, and alternatively-…

On an inverse problem for scalar conservation laws

We study in what sense one can determine the flux functions k = k(x) and f = f(u), k piecewise constant, in the scalar hyperbolic conservation law u(t) + (k(x)f (u))(x) = 0 by observing the solution u(t, center dot) of the Cauchy problem with suitable piecewise constant initial data u vertical bar(…

Kerr spacetime with an arbitrary mass quadrupole moment: geometric properties vs particle motion

Some examples of kinetic schemes whose diffusion limit is Il'in's exponential-fitting

This paper is concerned with diffusive approximations of some numerical schemes for several linear (or weakly nonlinear) kinetic models which are motivated by wide-range applications, including radiative transfer or neutron transport, run-and-tumble models of chemotaxis dynamics, and Vlasov-Fokker-…

Evaluation of HIV-1 and CD4+ T cell dynamic parameters in patients treated with genotypic resistance testing-guided HAART

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Steady-state invariance in high-order Runge-Kutta discretization of optimal growth models

This work deals with infinite horizon optimal growth models and uses the results in the Mercenier and Michel (1994a) paper as a starting point. Mercenier and Michel (1994a) provide a one-stage Runge-Kutta discretization of the above-mentioned models which preserves the steady state of the…

A two-weight Sobolev inequality for Carnot-Carathéodory spaces

Let X={X1,X2,...,Xm} be a system of smooth vector fields in R^n satisfying the Hörmander's finite rank condition. We prove the following Sobolev inequality with reciprocal weights in Carnot-Carathéodory space G associated to system X (1?BRK(x)dx?BR|u|tK(x)dx)1/t<=CR??1?BR1K(x)dx?BR|Xu|2K(x)dx??…

Permanence and global stability of a class of discrete epidemic models

In this paper we investigate the permanence of a system and give a sufficient condition for the endemic equilibrium to be globally asymptotically stable, which are the remaining problems in our previous paper (G. Izzo, Y. Muroya, A. Vecchio, A general discrete time model of population dynamics in…