ERA4TB-EUROPEAN REGIMEN ACCELERATOR FOR TUBERCULOSIS

L'European Tuberculosis Regimen Accelerator (ETBRA) ha l'obiettivo esplicito di sviluppare una nuova terapia combinata per il trattamento di tutte le forme di tubercolosi a partire da circa 20 derivazioni e farmaci candidati forniti da EFPIA. Poiché i dettagli di questi non sono ancora disponibili, implementeremo un algoritmo di sviluppo di farmaci agile che comporta la profilazione e la costruzione del portafoglio.

PRIN 3D-Phys

Principi fisici della stampa 3D multimateriale: intuizioni dalla fisica verso l'industria 4.0

La produzione additiva è considerata una delle tecnologie più potenti mai inventate, in quanto ha cambiato notevolmente design e produzione nella nuova Industria 4.0. Tuttavia, a causa della complessa interazione di tecniche e materiali di stampa 3D, la stampa multimateriale in cui sono presenti più fasi o composti potrebbe essere influenzata da fenomeni di agglomerazione o separazione di fase su scala nano-meso, portando a sistemi difettosi con proprietà disomogenee.

IPC - Individualized Paediatric Cure

Un'efficace medicina personalizzata per i tumori pediatrici deve affrontare una moltitudine di sfide, comprese le sfide dominio-specifiche. Per far ciò, il progetto IPC propone un approccio computazionale multicomprensivo, che combina diversi modelli, dall'apprendimento automatico ai modelli meccanicistici, per prevedere terapie standard e sperimentali ottimali per ogni bambino.

Level 2 processor and auxiliary data for ESA Version 8 final fullmission analysis of MIPAS measurements on ENVISAT

High quality long-term data sets of altitude-resolved measurements of the atmospheric composition areimportant because they can be used both to study the evolu-tion of the atmosphere and as a benchmark for future mis-sions. For the final ESA reprocessing of MIPAS (MichelsonInterferometer for Passive Atmospheric Sounding) on ENVISAT (ENViromental SATellite) data, numerous improve-ments were implemented in the Level 2 (L2) processor Op-timised Retrieval Model (ORM) version 8.22 (V8) and itsauxiliary data.

A moving boundary problem for reaction and diffusion processes in concrete: Carbonation advancement and carbonation shrinkage

The present work is devoted to modeling and simulation of the carbonation process in concrete. To this aim we introduce some free boundary problems which describe the evolution of calcium carbonate stones under the attack of $ {CO}_2 $ dispersed in the atmosphere, taking into account both the shrinkage of concrete and the influence of humidity on the carbonation process. Indeed, two different regimes are described according to the relative humidity in the environment.

Cassini and extra force constraints to nonminimally coupled gravity with a screening mechanism

We consider a nonminimally coupled curvature-matter gravity theory at the Solar System scale. Both a fifth force of Yukawa type and a further non-Newtonian extra force that arises from the nonminimal coupling are present in the solar interior and in the solar atmosphere up to interplanetary space. The extra force depends on the spatial gradient of space-time curvature R. The conditions under which the effects of such forces can be screened by the chameleon mechanism and be made consistent with Cassini measurement of parametrized post-Newtonian parameter gamma are examined.

The FORUM end-to-end simulator project: architecture and results

FORUM (Far-infrared Outgoing Radiation Understanding and Monitoring) will fly as the ninth ESA's Earth Explorer mission, and an end-to-end simulator (E2ES) has been developed as a support tool for the mission selection process and the subsequent development phases. The current status of the FORUM E2ES project is presented together with the characterization of the capabilities of a full physics retrieval code applied to FORUM data.
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