Three-stage multiscale modelling of the NMDA neuroreceptor

We present a new multistage method to study the N-Methyl-D-Aspartate (NMDA) neuroreceptor starting from the reconstruction of its crystallographic structure. Thanks to the combination of Homology Modelling, Molecular Dynamics and Lattice Boltzmann simulations, we analyse the allosteric transition of NDMA upon ligand binding and compute the receptor response to ionic passage across the membrane.

ROBustness In Network (robin): an R Package for Comparison and Validation of Communities

In network analysis, many community detection algorithms have been developed. However, their implementation leaves unaddressed the question of the statistical validation of the results. Here, we present robin (ROBustness In Network), an R package to assess the robustness of the community structure of a network found by one or more methods to give indications about their reliability.

Higher-order tail contributions to the energy and angular momentum fluxes in a two-body scattering process

The need for more and more accurate gravitational-wave templates requires taking into account all possible contributions to the emission of gravitational radiation from a binary system. Therefore, working within a multipolar-post-Minkowskian framework to describe the gravitational-wave field in terms of the source multipole moments, the dominant instantaneous effects should be supplemented by hereditary contributions arising from nonlinear interactions between the multipoles.

A Fractional-in-Time Prey-Predator Model with Hunting Cooperation: Qualitative Analysis, Stability and Numerical Approximations

A prey-predator system with logistic growth of prey and hunting cooperation of predators is studied. The introduction of fractional time derivatives and the related persistent memory strongly characterize the model behavior, as many dynamical systems in the applied sciences are well described by such fractional-order models. Mathematical analysis and numerical simulations are performed to highlight the characteristics of the proposed model.

The vortex-driven dynamics of droplets within droplets

Understanding the fluid-structure interaction is crucial for an optimal design and manufacturing of soft mesoscale materials. Multi-core emulsions are a class of soft fluids assembled from cluster configurations of deformable oil-water double droplets (cores), often employed as building-blocks for the realisation of devices of interest in bio-technology, such as drug-delivery, tissue engineering and regenerative medicine.

Anomaly detection in multichannel data using sparse representation in radwt frames

We introduce a new methodology for anomaly detection (AD) in multichannel fast oscillating signals based on nonparametric penalized regression. Assuming the signals share similar shapes and characteristics, the estimation procedures are based on the use of the Rational-Dilation Wavelet Transform (RADWT), equipped with a tunable Q-factor able to provide sparse representations of functions with different oscillations persistence. Under the standard hypothesis of Gaussian additive noise, we model the signals by the RADWT and the anomalies as additive in each signal.

Binary dynamics at the fifth and fifth-and-a-half post-Newtonian orders

Using the new methodology introduced in a recent paper [D. Bini, T. Damour, and A. Geralico, Phys. Rev. Lett. 123, 231104 (2019)], we present the details of the computation of the conservative dynamics of gravitationally interacting binary systems at the fifth post-Newtonian (5PN) level, together with its extension at the fifth-and-a-half post-Newtonian level. We present also the sixth post-Newtonian (6PN) contribution to the third-post-Minkowskian (3PM) dynamics.