Continuity properties of solutions to the p-Laplace system
A sharp integrability condition on the right-hand side of the p-Laplace system for all its solutions
to be continuous is exhibited. Their uniform continuity is also analyzed and estimates for their modulus
of continuity are provided. The relevant estimates are shown to be optimal as the right-hand side ranges in
classes of rearrangement-invariant spaces, such as Lebesgue, Lorentz, Lorentz-Zygmund, and Marcinkiewicz
spaces, as well as some customary Orlicz spaces.
Combining pathway identification and survival prediction via screening-network analysis
Motivation
Gene expression data from high-throughput assays, such as microarray, are often used to
predict cancer survival. However, available datasets consist of a small number of samples (n patients)
and a large number of gene expression data (p predictors). Therefore, the main challenge
is to cope with the high-dimensionality, i.e. p>>n, and a novel appealing approach is to use
screening procedures to reduce the size of the feature space to a moderate scale (Wu & Yin 2015,
Song et al. 2014, He et al. 2013).
Applications of network-based survival analysis methods for pathway detection in cancer
Gene expression data from high-throughput assays, such as
microarray, are often used to predict cancer survival. Available datasets
consist of a small number of samples (n patients) and a large number of
genes (p predictors). Therefore, the main challenge is to cope with the
high-dimensionality. Moreover, genes are co-regulated and their expression
levels are expected to be highly correlated. In order to face these
two issues, network based approaches can be applied.
Is this the right normalization? A diagnostic tool for ChIP-seq normalization
Background: Chip-seq experiments are becoming a standard approach for genome-wide profiling protein-DNA interactions, such as detecting transcription factor binding sites, histone modification marks and RNA Polymerase II occupancy. However, when comparing a ChIP sample versus a control sample, such as Input DNA, normalization procedures have to be applied in order to remove experimental source of biases. Despite the substantial impact that the choice of the normalization method can have on the results of a ChIP-seq data analysis, their assessment is not fully explored in the literature.
Rheologic and dynamic behavior of sheared vesicle suspensions
The rheology and dynamics of suspensions of fluid vesicles is investigated by a combination of molecular dynamics and mesoscale hydrodynamics simulations in two dimensions. The vesicle suspension is confined between two no-slip shearing walls. The flow behavior is studied as a function of the shear rate, the volume fraction of vesicles, and the viscosity ratio between inside and outside fluids. Results are obtained for the interactions of two vesicles, the intrinsic viscosity of the suspension, and the cell-free layer near the walls.
Two-dimensional performance of MIPAS observation modes in the upper-troposphere/lower-stratosphere
In this paper we analyze the performance of the three MIPAS (Michelson Interferometer for Passive Atmospheric Sounding) observation modes that sound the Upper-Troposphere/Lower-Stratosphere (UT/LS) region. The two-dimensional (2-D) tomographic retrieval approach is assumed to derive the atmospheric field of geophysical parameters. For each observation mode we have calculated the 2-D distribution of the information load quantifier relative to the main MIPAS targets.