Combining pathway identification and survival prediction via screening-network analysis

Motivation Gene expression data from high-throughput assays, such as microarray, are often used to predict cancer survival. However, available datasets consist of a small number of samples (n patients) and a large number of gene expression data (p predictors). Therefore, the main challenge is to cope with the high-dimensionality, i.e. p>>n, and a novel appealing approach is to use screening procedures to reduce the size of the feature space to a moderate scale (Wu & Yin 2015, Song et al. 2014, He et al. 2013).

New Results on Rational Approximation

First asymptotic relations of Voronovskaya-type for rational operators of Shepard-type are shown. A positive answer in some senses to a problem on the pointwise approximation power of linear operators on equidistant nodes posed by Gavrea, Gonska and Kacs is given. Direct and converse results, computational aspects and Gruss-type inequalities are also proved. Finally an application to images compression is discussed, showing the outperformance of such operators in some senses.

Time asymptotic high order schemes for dissipative BGK hyperbolic systems

We introduce a new class of finite differences schemes to approximate one dimensional dissipative semilinear hyperbolic systems with a BGK structure. Using precise analytical time-decay estimates of the local truncation error, it is possible to design schemes, based on the standard upwind approximation, which are increasingly accurate for large times when approximating small perturbations of constant asymptotic states. Numerical tests show their better performances with respect to those of other schemes.

A non-local rare mutations model for quasispecies and prisoner's dilemma: Numerical assessment of qualitative behaviour

An integro-differential model for evolutionary dynamics with mutations is investigated by improving the understanding of its behaviour using numerical simulations. The proposed numerical approach can handle also density dependent fitness, and gives new insights about the role of mutation in the preservation of cooperation.

CFD Maneuvering Prediction of a Twin Screw Vessel with Different Stern Appendages Configuration

The turning circle maneuver of a self-propelled tanker like ship model is numerically simulated through the integration of the unsteady Reynolds averaged Navier-Stokes (uRaNS) equations coupled with the equations of the motion of a rigid body. The solution is achieved by means of the unsteady RANS solver ?navis developed at CNR-INSEAN. The focus here is on the analysis of the maneuvering behavior of the ship with two different stern appendages configurations; namely, a twin screw with a single rudder and a twin screw, twin rudder with a central skeg.

Bioinspired synthesis of CaCO3 superstructures through a novel hydrogel composite membranes mineralization platform: a comprehensive view

Hydrogel composite membranes (HCMs) are used as novel mineralization platforms for the bioinspired synthesis of CaCO3 superstructures. A comprehensive statistical analysis of experimental results revealed quantitative relationships between crystallization conditions and crystal texture and the strong selectivity toward complex morphologies when monomers bearing carboxyl and hydroxyl groups are used together in the hydrogel synthesis in HCMs.

Numerical solution of the Perspective Shape- from-Shading problem

We study the Perspective Shape from Shading problem from the numerical point of view pre- senting a simple algorithm to compute its solution. The scheme is based on a semi-Lagrangian approximation of the first order Hamilton-Jacobi equation related to the problem. The scheme is converging to the weak solution (in the viscosity sense) of the equation and allows to compute accurately regular as well as non regular solutions.